Heterogeneity of teta-activity and its sources in Parkinson's disease

N. Kozhemiako, A. Cherninskyi, I. Zyma, N. Karasevich, S. Kryzhanovskyi
Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; D.F.Chebotarev State Institute of Gerontology NAMS of Ukraine, Kyiv; D.F.Chebotarev State Institute of Gerontology NAMS of Ukraine, Kyiv

Abstract


The risk of appearance of non-motor symptoms including cognitive dysfunctions is increased while Parkinson's disease (PD) progression. A lot of EEG-studies have shown that the degree of cognitive impairments correlates with increasing of θ-band spectral power. The aim of this research was to investigate the cause of such phenomenon. The resting state EEGs of 30 patients with PD and 30 healthy volunteers 45-65 years old were analyzed. We have established that the increasing of θ power has heterogenic nature. First reason is greater activity of existing θ-generators, mainly in posterior cingulate cortex. The other reason is the decreasing of the dominant resting state rhythm's frequency, which can affect the values of spectral power of θ-band.


Keywords


teta( θ)-activity, Parkinson's disease, slowing of the resting state rhythm

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DOI: http://dx.doi.org/10.17721/2616_6410.2016.20.80-85

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