Definition of optimum scheme of cocarnit injection for rats with polyneuropathy following diabetis induced by tenzoalogometric method

N. Nikitina, S. Beregovyi, L. Stepanova, O. Kabanov
ESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, Kyiv; ESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, Kyiv; ESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, Kyiv; ESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, Kyiv

Abstract


The change of pain threshold in rats with diabetic polyneuropathy and the efficacy of Cocarnit in the treatment of this complication has been studied, and the optimal scheme of drug administration has been determined. It is established that daily administration of the drug for 9 and 12 days has a positive effect on the nerve conduction and returns to the normal response to the pain stimulus.


Keywords


threshold of pain sensitivity, diabetic polyneuropathy, Сocarnit

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References


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DOI: http://dx.doi.org/10.17721/2616_6410.2017.23.37-42

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