M. Khrabko, R. Fedoruk, S. Kropuvka
; Institute of animal biology NAAS, Lviv, Ukraine; Institute of animal biology NAAS, Lviv, Ukraine


The aim of research was to study the effect of different doses of Ge citrate, obtained by nanotechnology method and chemically synthesized, the activity of their immune and antioxidant system blood of pregnant female rats. Research performed on rats F1 which were watering Ge citrate obtained by nanotechnology method in doses 10 (II), 20 (III), 200 (IV) mcg Ge and chemically synthesized Ge citrate in dose 2,000 (V) mg Ge. Ge citrate watering during the milk-feeding period up to 18-20 days of pregnancy. Not the same directional effect Ge citrate parameters of immune and antioxidant systems with increased content of immune globulin, glycoproteins and activity of enzymes of antioxidant protection that is more pronounced in females receiving 20 mcg Ge. Established inhibitory effect of Ge citrate 2 mg/kg albumin content and threeacylglycerol, amid increasing the level of creatinine in the blood of pregnant females V group which may indicate a decrease of albumin-transport function of filtering and absorption the ability of the kidneys.


germanium citrate; blood; rat;, immunophysiology


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