The changes in protein content of blood serum and esophageal homogenate under acid burn development in immature rats

T. Koval, T. Ischuk, Ya. Raetska
; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine

Abstract


The steady increase of the number of chemical esophagus burns is noted over the past tenth anniversary. The esophageal acid burns are seen frequently in children ages 1 to 8 years. The chemical injuries sights are characterized by increase synthesis and degradation of proteins and scar formation. The cicatricial changes of the esophagus, developing as a result of burns, remain one of the most difficult problems of physiological functions maintaining. Despite of numerous studies, there are many insufficiently studied issues of esophagus burn healing and scarring process at the cellular and molecular level. Further study of the esophageal burns healing process would be useful to create effective approaches to prevention of scarring formation in esophagus.

Keywords


burn the esophagus; protein fraction; electrophoresis

References


Кузнецова O. М., Кушлинский Н. Е., Березов Т. Т. Фактор роста эндотелия сосудов: особенности секреции в костной ткани в норме и при патологии. Биомедицинская химия. 2003; №49: 60–373.

Мухоедова Т.В., Жидкова О.В. Протеины теплового шока в противоинфекционной и полиорганной защите. Патология кровообращения и кардиохирургия. 2010; №4: 69-73.

Раєцька Я.Б., Іщук Т.В., Савчук О.М., Остапченко Л.І. Експериментальна модель лужного опіку I та II-го ступеню стравоходу у статевонезрілих щурів. Науковий вісник Чернівецького національного університету імені Юрія Федьковича. Біологія. 2014; Т.6: 129-132.

Фисталь Э.Я., Козинец Г.П., Самойленко Г.Е. и др. Комбустиология. Учебник: Донецк. 2005: 315 с.

Bruen K., Campbell C., Schooler W. et al. Real-time monitoring of keratin 5 expression during burn re-epithelialization. Journal of Surgical Research. 2004; №120: 12–20.

Fayazov A. D., Shukurov S. I., Shukurov B. I. et al. Disorders of the immune system in severely burned patients. Ann Burns Fire Disasters. 2009; №22: 121–130.

Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970; №227: 680–685.

Ramakrishnan O., Prathiba V., Sridhar K. et al. Expression of keratin in post burn scars and keloids. Annals of Burns and Fire Disasters. 1995; №8: 6–9. Надійшла




DOI: http://dx.doi.org/10.17721/2616_6410.2017.22.36-39

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