Intensity of free radical processes in cartilage of rats with collagen-induced arthritis

E. Tihova, O. Bernyk, O. Savchuk, K. Dvorshchenko, L. Ostapchenko
Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv

Abstract


Products of free radical oxidation and antioxidant enzymes in rats with collagen-induced arthritis were studied. It was established, that under experimental model of arthritis in rat cartilage the content of superoxide anion radical, peroxide and TBA-active compounds and the activity of antiradical enzymes superoxide dismutase and catalase increased.

Keywords


inflammation of the joints, cartilage, oxidative stress, reactive oxygen species, antioxidant enzymes.

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References


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DOI: http://dx.doi.org/10.17721/2616_6410.2016.21.27-30

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