Comparative analysis of therapeutic effects from introduction of Bionanocompomposite and fenugreek-based Orlistat on markers of endogenous intoxication in rats with experimental obesity

Ye. Goloborodko, T. Ishchuk, T. Synel'nyk, V. Konopelniuk
Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv; Taras Shevchenko National University of Kyiv, Kyiv


It were studied the markers of endogenous intoxication in males rats under development of the obesity induced by consumption of high-calorie diet. The acticle presents comparative analysis of the therapeutic effects with introduction bionanocomposite and orlistat which basic on the indicators of endogenous intoxication. It was shown increase the level of middle-mass molecules and oligopeptides in serum rats with obesity during of the research and normalization of these indicators after introduction bionanocomposit animals with obesity.


obesity, bionanocomposite, orlistat, intoxication

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